Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a form of transcranial magnetic stimulation (TMS), reduced severe depression symptoms in 90% of participants in a small trial, researchers reported in The American Journal of Psychiatry. 

In this podcast, Nolan R. Williams, MD, discusses clinical and neuroscience-related reasons for the study’s approach, goals of the study, how the trial was conducted, key findings, and possible clinical applications.

Dr. Williams is an Assistant Professor in the Department of Psychiatry and Behavioral Sciences and Director of the Brain Stimulation Lab at the Stanford University School of Medicine in California. He has a broad background in neuropsychiatry and is double board-certified in both neurology and psychiatry. In addition, he has specific training and clinical expertise in the development of brain stimulation methodologies under Mark George, MD.